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In vitro studies confirm that linagliptin suppresses the proliferation of several tumor cell lines, including colorectal cancer HCT116, breast cancer MCF-7, and liver cancer HepG2, via mechanisms that involve cell cycle arrest and apoptosis induction [96]
Once-weekly subcutaneous amycretin up to 60 mg for 36 weeks
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In human tests, an oral dosage of 250 g/kg body weight resulted in a reduction of two injections per day [34]
