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Interestingly, a smaller BMO diameter appears to correspond to fewer systemic risk factors

For women, both medications can affect menstrual cycles

The latter enrolled 190 patients with obesity (mean age 54.4 years, mean BMI 36.1 kg/m 2 ) and biopsy-proven MASH and moderate-to-severe fibrosis regardless of the presence of T2D, showing a BW reduction of 10.7%, 13.3%, 15.6% and 0.8% at 52 weeks with tirzepatide 5 mg, 10 mg, 15 mg and placebo, respectively 39

Tirzepatide is a GIP and GLP-1 receptor antagonist that should be approved for weight loss this year by the FDA
Am J Physiol Heart Circ Physiol 2011;300:H2H12
