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These results were presented at the 2025 European Congress on Obesity in Malaga, Spain, and published in the New England Journal of Medicine

Real-World Reports of Palpitations After a medication is approved, doctors and patients report side effects through systems like the FDA Adverse Event Reporting System (FAERS)

Rare for both and, in the weight-loss trials, no higher than placeboroughly 0.3% on Wegovy and 0.2% on Zepbound

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The intake captures personal AND family history for medullary thyroid cancer and MEN-2, runs an opt-out exclusionary block on end-stage kidney/liver disease, suicidality, active cancer, organ transplant and severe GI disease, and includes a structured substance/opioid screen with a three-month opiate window requiring free-text date range, name, dose and frequency