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doi: 10.1016/j.cell.2012.08.024
Among all the harmful compounds are some polycyclic aromatic chemical compounds that cause the most damage to our health
Between 2004 and 2014, young adults continued to smoke menthol cigarettes at increasing levels even as overall smoking rates declined
Theoretically, nicotine could be harmful based on its chemical reactivity as carcinogens such as nitrosamines modify DNA or through pharmacological means with nicotine interacting with its biological target, the nicotinic acetylcholine receptor
Moreover, NF-kB is a major pro-inflammatory transcription factor activated by inflammatory cytokines and ROS, which is one of the key roles in the formation of EMT [128, 129]
