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Description
SPIGFD in these patients were defined by phenotypic and biochemical characteristics and they were treated with recombinant human (rh)IGF-1 in one of the clinical trials leading to approval of this therapy, as described later

10.1038/nrn1683 Nat
| CAPS Plastic Surgery, Dermatology, MedSpa, & Wellness Center

Oxidative stress has a negative impact on both bone tissue quality and bone catabolism [55]

Group 1 received a saline injection as a control
