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Merrill JT, June J, Koumpouras F et al (2018) Top-line results of a phase 2, double-blind, randomized, placebo-controlled study of a reversible B cell inhibitor, XmAb5871, in systemic lupus erythematosus (SLE)
It results in impaired conversion of pyruvate to acetyl-CoA
[DOI] [PubMed] [Google Scholar] 67.Jelovac N., Sikiric P., Rucman R., Petek M., Marovic A., Perovic D., Seiwerth S., Mise S., Turkovic B., Dodig G., et al
Biosynthesis : It provides carbon and nitrogen for building nucleotides, lipids, and proteins
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