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such reactions have limited positional and no stereo-specificity

For instance, secondary A829P KIT mutation renders melanoma cells resistant to imatinib but has no influence on nilotinib and dasatinib, while the T670I KIT mutation exhibits resistance to imatinib, nilotinib as well as dasatinib, but can still be suppressed by sunitinib (154)

Patients colonized with toxin-producing strains are at risk for disease, particularly if exposed to antibiotics

Measurements of osmolality or osmolarity alone are not sufficient to characterize the tonicity of a liquid

The treatment is quite comfortable and requires no anesthesia