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The emerging potential therapeutic strategies targeting immune-inflammatory interactionsincluding specific inflammatory pathway inhibitors, stem cell-based immunomodulatory therapy, and epigenetic regulationrepresent the future development direction of varicocele treatment (212, 213)

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Bianciardi L, Fichera M, Failla P et al (2016) MECP2 missense mutations outside the canonical MBD and TRD domains in males with intellectual disability

Abstract L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract

The supplements with the strongest evidence for supporting fertility include folic acid, vitamin B12, omega-3 fatty acids, and CoQ10 in specific cases, such as advanced maternal age or reduced ovarian reserve