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1- 4 A disease-modifying therapy that can slow the progression of PD, and delay the onset of dementia, is an urgent unmet need

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When tesamorelin binds to GHRH receptors on pituitary somatotroph cells, it triggers the adenylate cyclase-cAMP signaling cascade, which stimulates the synthesis and secretion of endogenous growth hormone in pulsatile bursts that mirror the body natural rhythm

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doi: 10.1179/135100009X392539 294 WilliamsB
