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In the future, this mechanism might also extend to novel treatments of other neuroinflammatory and neurodegenerative conditions. Additional authors on the study include Deepa Jonnalagadda, Manisha Ray, Clayton Ellington and Richard Rivera, all at Sanford Burnham Prebys, Aran Groves, Sanford Burnham Prebys and UC San Diego

An estrogen receptor beta-selective agonist inhibits non-alcoholic steatohepatitis in preclinical models by regulating bile acid and xenobiotic receptors

Secretory phospholipase A2 may act together with bactericidal/permeability-increasing protein (BPI), also present in eosinophil granules, in microorganism defense

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Examination of cultures including by flow cytometry showed that the cells (Figure S2B) tended to form clumps in the presence of 150 g/ml 5-FOA, which could skew the OD-based normalization of cellular GSH level measurements